Rolf Graf Selected Research

Lithostathine

12/2021	Pancreatic Stone Protein Predicts Sepsis in Severely Burned Patients Irrespective of Trauma Severity: A Monocentric Observational Study.
7/2021	Incidence and Time Point of Sepsis Detection as Related to Different Sepsis Definitions in Severely Burned Patients and Their Accompanying Time Course of Pro-Inflammatory Biomarkers.
1/2021	Accuracy of pancreatic stone protein for the diagnosis of infection in hospitalized adults: a systematic review and individual patient level meta-analysis.
1/2021	Response of routine inflammatory biomarkers and novel Pancreatic Stone Protein to inhalation injury and its interference with sepsis detection in severely burned patients.
4/2020	Pancreatic stone protein - sepsis and the riddles of the exocrine pancreas.
1/2020	Expression of Pancreatic Stone Protein is Unaffected by Trauma and Subsequent Surgery in Burn Patients.
6/2017	Elevated serum level of pancreatic stone protein/regenerating protein (PSP/reg) is observed in diabetic kidney disease.
5/2017	The pancreas responds to remote damage and systemic stress by secretion of the pancreatic secretory proteins PSP/regI and PAP/regIII.
11/2015	Normal values for pancreatic stone protein in different age groups.
9/2015	Prognostication of Mortality in Critically Ill Patients With Severe Infections.

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Rolf Graf Research Topics

Disease

23	Neoplasms (Cancer) 03/2022 - 06/2006
15	Pancreatitis 03/2022 - 05/2006
15	Inflammation (Inflammations) 12/2021 - 09/2003
14	Sepsis (Septicemia) 12/2021 - 05/2009
9	Chronic Pancreatitis 01/2021 - 06/2003
9	Ischemia 08/2018 - 05/2003
8	Infections 12/2021 - 05/2009
8	Reperfusion Injury 01/2020 - 03/2007
6	Wounds and Injuries (Trauma) 12/2021 - 05/2003
6	Necrosis 03/2014 - 08/2003
5	Fibrosis (Cirrhosis) 03/2022 - 03/2011
5	Liver Failure 01/2020 - 12/2012
4	Burns 12/2021 - 01/2020
4	Neoplasm Metastasis (Metastasis) 09/2021 - 07/2006
4	Colorectal Neoplasms (Colorectal Cancer) 09/2021 - 03/2011
4	Metaplasia 01/2020 - 12/2015
4	Autoimmune Pancreatitis 11/2017 - 11/2012
4	Type 2 Diabetes Mellitus (MODY) 04/2015 - 07/2012
4	Cholestasis 11/2013 - 05/2006
3	Hypertrophy 01/2021 - 05/2008
3	Hypoxia (Hypoxemia) 01/2021 - 10/2016
3	Weight Gain 01/2021 - 12/2012
3	Fatty Liver 01/2020 - 11/2007
3	Colonic Neoplasms (Colon Cancer) 11/2017 - 07/2008
3	Pancreatic Diseases (Pancreatic Disease) 04/2015 - 05/2009
2	Body Weight (Weight, Body) 03/2022 - 11/2013
2	Pain (Aches) 01/2021 - 01/2018
2	Pancreatic Neoplasms (Pancreatic Cancer) 01/2019 - 12/2016
2	Heart Arrest (Cardiac Arrest) 12/2014 - 11/2013
2	Mason-Type Diabetes 06/2013 - 07/2012
2	Hepatocellular Carcinoma (Hepatoma) 04/2010 - 10/2009
2	Hepatitis 10/2009 - 07/2008
1	Carcinogenesis 01/2022
1	Clinical Deterioration 12/2021
1	Critical Illness (Critically Ill) 12/2021
1	Obesity 01/2021

Drug/Important Bio-Agent (IBA)

24	LithostathineIBA 12/2021 - 06/2006
19	Proteins (Proteins, Gene)FDA Link 03/2022 - 05/2004
16	Biomarkers (Surrogate Marker)IBA 12/2021 - 05/2006
11	CeruletideIBA 03/2022 - 05/2006
10	Serotonin (5 Hydroxytryptamine)IBA 09/2021 - 02/2007
9	C-Reactive ProteinIBA 07/2021 - 07/2012
8	ProcalcitoninIBA 12/2021 - 07/2012
4	Amylases FDA Link 03/2022 - 05/2006
4	LipidsIBA 01/2020 - 11/2007
4	Adenosine Triphosphate (ATP)IBA 01/2020 - 02/2006
4	Interleukin-6 (Interleukin 6)IBA 03/2014 - 05/2008
3	Hemoglobins (Hemoglobin)IBA 01/2021 - 10/2016
3	inositol trispyrophosphateIBA 01/2021 - 12/2016
3	dicarboxydine (DCD)IBA 12/2014 - 11/2009
3	Lymphotoxin-alpha (Lymphotoxin)IBA 04/2014 - 10/2009
3	Pancreatitis-Associated ProteinsIBA 03/2014 - 01/2009
3	Acute-Phase Proteins (Acute-Phase Protein)IBA 03/2014 - 01/2009
3	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 07/2012 - 04/2004
3	Heat-Shock Proteins (Heat-Shock Protein)IBA 02/2011 - 06/2003
2	Amino Acid Transport Systems (Amino Acid Transporter)IBA 03/2022 - 09/2013
2	EnzymesIBA 03/2022 - 11/2012
2	TOR Serine-Threonine KinasesIBA 03/2022 - 01/2017
2	Messenger RNA (mRNA)IBA 03/2022 - 12/2007
2	Monomeric GTP-Binding ProteinsIBA 09/2021 - 11/2018
2	Glucose (Dextrose)FDA LinkGeneric 01/2021 - 03/2007
2	Oxygen (Dioxygen)IBA 01/2021 - 11/2017
2	AutoantibodiesIBA 11/2020 - 11/2012
2	Unsaturated Fatty Acids (Polyunsaturated Fatty Acids)IBA 01/2020 - 04/2007
2	Thyroid HormonesIBA 01/2019 - 12/2015
2	Biological ProductsIBA 01/2019 - 10/2016
2	Histone Deacetylases (Histone Deacetylase)IBA 01/2018 - 11/2017
2	entinostat (MS 275)IBA 01/2018 - 11/2017
2	Protein Isoforms (Isoforms)IBA 11/2017 - 05/2004
2	CateninsIBA 01/2017 - 02/2015
2	Antineoplastic Agents (Antineoplastics)IBA 10/2016 - 11/2012
2	Transcription Factors (Transcription Factor)IBA 02/2016 - 07/2012
2	BilirubinIBA 11/2013 - 03/2011
2	Proliferating Cell Nuclear Antigen (PCNA)IBA 12/2012 - 07/2006
2	Interleukin-1beta (Interleukin 1 beta)IBA 07/2012 - 05/2008
2	Bile Acids and Salts (Bile Acids)IBA 07/2012 - 03/2011
2	Aspartate Aminotransferases (Aspartate Transaminase)IBA 07/2012 - 03/2011
2	CytokinesIBA 10/2009 - 05/2008
2	Omega-3 Fatty Acids (Omega 3 Fatty Acids)IBA 11/2007 - 04/2007
1	Leucine (L-Leucine)FDA Link 03/2022
1	Large Neutral Amino Acid-Transporter 1IBA 03/2022
1	telotristatIBA 09/2021
1	Glutamine (L-Glutamine)FDA Link 09/2021
1	Fluoxetine (Prozac)FDA LinkGeneric 09/2021
1	Immune Checkpoint InhibitorsIBA 09/2021
1	B7-H1 AntigenIBA 09/2021
1	Programmed Cell Death 1 ReceptorIBA 09/2021
1	Buprenorphine (Subutex)FDA LinkGeneric 01/2021
1	Tramadol (K315)FDA LinkGeneric 01/2021
1	Analgesics (Analgesic Drugs)IBA 01/2021

Therapy/Procedure

14	Hepatectomy 01/2020 - 07/2006
7	Therapeutics 12/2021 - 06/2006
7	Ligation 01/2019 - 07/2006
6	Liver Transplantation 08/2018 - 08/2003
4	Injections 03/2022 - 01/2018
4	Drug Therapy (Chemotherapy) 01/2021 - 03/2011
3	Critical Care (Surgical Intensive Care) 12/2021 - 07/2012
3	Intraperitoneal Injections 09/2021 - 02/2007
3	Transplantation 07/2010 - 05/2003
1	Radiotherapy 01/2021